SCHEMBL29587172

SCHEMBL29587172

CC(C)=NNC(=O)c1cc2ccccc2cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR39 O43194 1/20 0.67
MEN1 O00255 8/20 0.65
KMT2A Q03164 8/20 0.65
MAPT P10636 7/20 0.65
POLB P06746 6/20 0.65
GAA P10253 6/20 0.65
KDM4E B2RXH2 5/20 0.65
RAB9A P51151 4/20 0.65
RECQL P46063 4/20 0.65
THRB P10828 4/20 0.65
NPC1 O15118 3/20 0.65
USP2 O75604 3/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
PLA2G1B P04054 1/20 0.65
ALOX12 P18054 1/20 0.65
BLM P54132 1/20 0.65
MCL1 Q07820 1/20 0.65
ESR2 Q92731 1/20 0.65
ATG4B Q9Y4P1 1/20 0.65
HSP90AA1 P07900 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1278875 1.00 GPR39 (0.67) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL30240764 0.85 GPR39 (0.81) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL1278646 0.85 MEN1 (0.66) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL30240801 0.85 MEN1 (0.66) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL5149471 0.85 GPR39 (0.81) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL1278645 0.85 MEN1 (0.66) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL6634348 0.85 GPR39 (0.81) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL5149465 0.85 GPR39 (0.81) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL6634707 0.85 MEN1 (0.66) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL2278849 0.83 GAA (0.71) GPR39MEN1KMT2AMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114521202-B Rubber composition, method for producing same, and tire for engineering vehicle 横滨橡胶株式会社 2024-01-26 CN disclosed
US-20230073273-A1 RUBBER COMPOSITION, METHOD FOR PREPARING SAME, AND TIRE FOR CONSTRUCTION VEHICLE THE YOKOHAMA RUBBER CO., LTD. (JP) 2023-03-09 US disclosed
CN-111094428-B Rubber composition 住友化学株式会社 2022-07-15 CN disclosed
CN-114521202-A Rubber composition, method for producing same, and tire for construction vehicle 横滨橡胶株式会社 2022-05-20 CN disclosed
WO-2022097606-A1 RUBBER COMPOSITION FOR TIRES 横浜ゴム株式会社 2022-05-12 WO disclosed