SCHEMBL5149471

SCHEMBL5149471

CC(=NNC(=O)c1cc2ccccc2cc1O)c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR39 O43194 1/20 0.81
POLB P06746 7/20 0.67
RAB9A P51151 7/20 0.67
NPC1 O15118 6/20 0.67
MEN1 O00255 6/20 0.67
KMT2A Q03164 6/20 0.67
MAPT P10636 6/20 0.67
GAA P10253 5/20 0.67
THRB P10828 3/20 0.67
USP2 O75604 3/20 0.67
OGG1 O15527 1/20 0.67
HSP90AA1 P07900 1/20 0.67
OPRK1 P41145 1/20 0.67
KDM4E B2RXH2 4/20 0.65
RECQL P46063 3/20 0.65
TDP1 Q9NUW8 2/20 0.65
MAPK1 P28482 1/20 0.65
SMN1; SMN2 Q16637 3/20 0.60
PLA2G1B P04054 1/20 0.60
ALOX12 P18054 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6634348 1.00 GPR39 (0.81) GPR39POLBRAB9ANPC1MEN1
SCHEMBL30240764 1.00 GPR39 (0.81) GPR39POLBRAB9ANPC1MEN1
SCHEMBL5149465 1.00 GPR39 (0.81) GPR39POLBRAB9ANPC1MEN1
SCHEMBL12443564 0.92 GPR39 (0.81) GPR39POLBRAB9ANPC1MEN1
SCHEMBL14983911 0.89 GPR39 (0.77) GPR39POLBRAB9ANPC1MEN1
SCHEMBL29587172 0.85 GPR39 (0.67) GPR39POLBRAB9ANPC1MEN1
SCHEMBL1278875 0.85 GPR39 (0.67) GPR39POLBRAB9ANPC1MEN1
SCHEMBL23719304 0.82 RAB9A (0.80) POLBRAB9ANPC1MEN1KMT2A
SCHEMBL29392673 0.81 GPR39 (0.66) GPR39POLBRAB9ANPC1MEN1
SCHEMBL18479801 0.81 MAPT (1.00) GPR39POLBRAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023095850-A1 STEEL CORD-RUBBER COMPOSITE, MANUFACTURING METHOD FOR STEEL CORD-RUBBER COMPOSITE, AND TIRE 株式会社ブリヂストン 2023-06-01 WO disclosed
CN-111537476-B Ni based on N' - (1, 3 dimethylbutylidene) -3-hydroxy-naphthoylhydrazone fluorescent probes 2+ Method of measurement of 衡阳师范学院 2023-01-10 CN disclosed
CN-111537476-A Ni based on N' - (1,3 dimethylbutylidene) -3-hydroxy-naphthoylhydrazone fluorescent probes2+Method of measurement of 衡阳师范学院 2020-08-14 CN disclosed
US-9890267-B2 Rubber composition for tires and pneumatic tire BRIDGESTONE CORPORATION (JP) 2018-02-13 US disclosed
EP-2977401-B1 RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2017-06-14 EP disclosed
US-9617404-B2 Rubber composition, conveyor belt rubber composition, conveyor belt, and belt conveyor device BRIDGESTONE CORPORATION (JP) 2017-04-11 US disclosed
US-20160122519-A1 RUBBER COMPOSITION, CONVEYOR BELT RUBBER COMPOSITION, CONVEYOR BELT, AND BELT CONVEYOR DEVICE BRIDGESTONE CORPORATION (JP) 2016-05-05 US disclosed
EP-2977401-A1 RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2016-01-27 EP disclosed
US-20160017124-A1 RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2016-01-21 US disclosed
US-20070157846-A1 Antirust composition OTSUKA CHEMICAL CO., LTD. (JP) 2007-07-12 US disclosed
EP-1717350-A1 ANTIRUST COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2006-11-02 EP disclosed
EP-0909788-B1 RUBBER COMPOSITION AND PNEUMATIC TIRES BRIDGESTONE CORP (JP) 2004-12-01 EP disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed