Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR39 | O43194 | 1/20 | 0.81 |
| ▸ | POLB | P06746 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 5/20 | 0.67 |
| ▸ | THRB | P10828 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 3/20 | 0.67 |
| ▸ | OGG1 | O15527 | 1/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634348 | 1.00 | GPR39 (0.81) | GPR39POLBRAB9ANPC1MEN1 | |
| SCHEMBL5149471 | 1.00 | GPR39 (0.81) | GPR39POLBRAB9ANPC1MEN1 | |
| SCHEMBL5149465 | 1.00 | GPR39 (0.81) | GPR39POLBRAB9ANPC1MEN1 | |
| SCHEMBL12443564 | 0.92 | GPR39 (0.81) | GPR39POLBRAB9ANPC1MEN1 | |
| SCHEMBL14983911 | 0.89 | GPR39 (0.77) | GPR39POLBRAB9ANPC1MEN1 | |
| SCHEMBL29587172 | 0.85 | GPR39 (0.67) | GPR39POLBRAB9ANPC1MEN1 | |
| SCHEMBL1278875 | 0.85 | GPR39 (0.67) | GPR39POLBRAB9ANPC1MEN1 | |
| SCHEMBL23719304 | 0.82 | RAB9A (0.80) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL29392673 | 0.81 | GPR39 (0.66) | GPR39POLBRAB9ANPC1MEN1 | |
| SCHEMBL18479801 | 0.81 | MAPT (1.00) | GPR39POLBRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169736-B1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORP (JP) | 2024-11-27 | — | — | EP | disclosed |
| US-20230312882-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2023-10-05 | — | — | US | disclosed |
| EP-4169736-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2023-04-26 | — | — | EP | disclosed |
| CN-115702200-A | Rubber composition and tire | 株式会社普利司通 | 2023-02-14 | — | — | CN | disclosed |