Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 12/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17288014 | 0.90 | KMT2A (0.61) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3830414 | 0.85 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3826986 | 0.80 | TSHR (0.52) | MEN1KMT2ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL17429824 | 0.79 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3825700 | 0.78 | MAPT (0.48) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3830845 | 0.78 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL10020928 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL4743736 | 0.76 | MEN1 (0.80) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL8072839 | 0.76 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL27913467 | 0.72 | MEN1 (0.89) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246158-A1 | ANTIOXIDANTS | LPO, GPX1, GPX4 | MEN1 2805/4885KMT2A 2864/4885SMN1; SMN2 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.