Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826214 | 0.86 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1PRKCAPRKCDPRSS1 | |
| SCHEMBL3826986 | 0.83 | TSHR (0.52) | KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1 | |
| SCHEMBL3830414 | 0.80 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1 | |
| SCHEMBL17288014 | 0.78 | KMT2A (0.61) | KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1 | |
| SCHEMBL12799441 | 0.78 | MEN1 (0.51) | KMT2ASMN1; SMN2MEN1L3MBTL1ALDH1A1 | |
| SCHEMBL28030230 | 0.75 | LMNA (0.58) | L3MBTL1ALDH1A1KDM4EGAAPRKCA | |
| SCHEMBL63237 | 0.75 | LMNA (0.58) | L3MBTL1ALDH1A1KDM4EGAAPRKCA | |
| SCHEMBL913893 | 0.75 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1KDM4EPOLBPRKCA | |
| SCHEMBL17907462 | 0.74 | LMNA (0.56) | L3MBTL1ALDH1A1KDM4EGAAPOLB | |
| SCHEMBL22684926 | 0.74 | LMNA (0.56) | L3MBTL1ALDH1A1KDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010294-B1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | claimed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | claimed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | claimed |
| CN-101437579-B | Antioxidant agent | MERCK PATENT GMBH | 2012-11-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246158-A1 | ANTIOXIDANTS | LPO, GPX1, GPX4 | KMT2A 2864/4885SMN1; SMN2 1726/4885MEN1 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.