Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913467 | 0.94 | MEN1 (0.89) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22938967 | 0.90 | MEN1 (0.81) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL39206 | 0.89 | KMT2A (1.00) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22939653 | 0.88 | MEN1 (0.77) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10061939 | 0.87 | MEN1 (0.78) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL13977801 | 0.87 | MEN1 (0.78) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7846776 | 0.87 | MEN1 (0.78) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL17212260 | 0.87 | ALDH1A1 (0.81) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL8072839 | 0.86 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2319068 | 0.86 | MEN1 (0.76) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018065359-A1 | BARBITURIC ACID DERIVATIVES AS SELF-TANNING SUBSTANCES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | WO | disclosed |
| US-20150306002-A1 | 3-HYDROXY-4-OXO-4H-PYRAN- OR 3-HYDROXY-4-OXO-1,4-DIHYDROPYRIDINE DERIVATIVES AS PROTEIN-ADHESIVE ACTIVE SUBSTANCES | MERCK PATENT GMBH (DE) | 2015-10-29 | — | — | US | disclosed |
| US-8481775-B2 | Method for improving the color index of organopolysiloxanes | DSM IP ASSETS B.V. (NL) | 2013-07-09 | — | — | US | disclosed |
| US-20120121524-A1 | PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS | MUELLER STEFAN (DE) | 2012-05-17 | — | — | US | disclosed |
| US-8119107-B2 | Photo-stable cosmetic or dermatological compositions | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20100143272-A1 | Photo-stable cosmetic or dermatological compositions | CIBA SPECIALTY CHEMICALS CORPORATION | 2010-06-10 | — | — | US | disclosed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306002-A1 | 3-HYDROXY-4-OXO-4H-PYRAN- OR 3-HYDROXY-4-OXO-1,4-DIHYDROPYRIDINE DERIVATIVES AS PROTEIN-ADHESIVE ACTIVE SUBSTANCES | S100A4, CUTA, OCIAD1 | MEN1 2911/4885KMT2A 4159/4885SMN1; SMN2 4821/4885 |
| US-20120121524-A1 | PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS | NISCH, CUTA, MITF | MEN1 2580/4885KMT2A 2049/4885SMN1; SMN2 3366/4885 |
| US-20090246158-A1 | ANTIOXIDANTS | LPO, GPX1, GPX4 | MEN1 2805/4885KMT2A 2864/4885SMN1; SMN2 1726/4885 |
| US-20100143272-A1 | Photo-stable cosmetic or dermatological compositions | DBF4, CUTA, ARSA | MEN1 975/4885KMT2A 742/4885SMN1; SMN2 3058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.