SCHEMBL12802427

SCHEMBL12802427

[Li]C([SiH2]c1ccccc1)(N(CC)CC)N(CC)CC

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12802578 0.77 KCNN4 (0.39) TSHRALDH1A1
SCHEMBL7033571 0.69 MAPK1 (0.33) TSHRALDH1A1
SCHEMBL2269750 0.67 MEN1 (0.37) TSHRALDH1A1
SCHEMBL15147452 0.66 RIPK1 (0.35) TSHRALDH1A1TP53
SCHEMBL27943103 0.66 TP53 (0.35) TSHRALDH1A1TP53
SCHEMBL2103612 0.65 ADRA2B (0.40) ALDH1A1
SCHEMBL2103219 0.65 CHRM1 (0.33)
SCHEMBL2269712 0.64 TP53 (0.38) TSHRALDH1A1GLATP53
SCHEMBL2102750 0.63 PGR (0.34) ALDH1A1
SCHEMBL1254751 0.63 MAPK1 (0.36) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9587042-B2 Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-07 US disclosed
US-8835564-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-16 US disclosed
US-20140088256-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
US-20120252966-A1 PROCESS FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-10-04 US disclosed