Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | DHPS | P49366 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397099 | 0.91 | MEP1B (0.38) | MEP1BDHPSKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3321728 | 0.85 | DHPS (0.41) | MEP1BDHPSALDH1A1HTR1AHTR1D | |
| SCHEMBL1396996 | 0.83 | ALDH1A1 (0.38) | MEP1BDHPSKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1396995 | 0.80 | DHPS (0.41) | MEP1BDHPSKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3454505 | 0.77 | DHPS (0.36) | MEP1BDHPSKDM4EALDH1A1HSD17B10 | |
| SCHEMBL119198 | 0.76 | ALDH1A1 (0.42) | MEP1BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12808919 | 0.76 | MEP1B (0.34) | MEP1B | |
| SCHEMBL1114950 | 0.75 | TAS1R3 (0.38) | MEP1BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL119850 | 0.74 | ALDH1A1 (0.43) | MEP1BDHPSKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16712267 | 0.74 | ALDH1A1 (0.43) | MEP1BDHPSKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181098-B1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2011-03-02 | — | — | EP | disclosed |