Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115268 | 0.91 | TAS1R3 (0.39) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL117789 | 0.90 | TAS1R3 (0.40) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL119198 | 0.89 | ALDH1A1 (0.42) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL1115150 | 0.88 | MEP1B (0.39) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL716664 | 0.88 | TAS1R3 (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL29769728 | 0.87 | KDM4E (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL679753 | 0.87 | KDM4E (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL1397026 | 0.85 | TAS1R3 (0.38) | TAS1R3TAS1R1MEP1BALDH1A1ACLY | |
| SCHEMBL11913395 | 0.85 | TAS1R3 (0.36) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E | |
| SCHEMBL1654712 | 0.84 | MEP1B (0.38) | TAS1R3TAS1R1MEP1BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279178-B1 | 2-(substituted phenyl)-6-hydroxy- or alkoxy-5-substituted-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2015-05-20 | — | — | EP | claimed |
| EP-2279178-B1 | 2-(substituted phenyl)-6-hydroxy- or alkoxy-5-substituted-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2015-05-20 | — | — | EP | disclosed |
| EP-2279178-A1 | 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2011-02-02 | — | — | EP | disclosed |
| US-7833940-B2 | 2-(substituted phenyl)-6-hydroxy or alkoxy-5-substituted-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-20090264293-A1 | 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-10-22 | — | — | US | disclosed |
| WO-2009129291-A1 | 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264293-A1 | 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, HPD, DDC | TAS1R3 1157/4885TAS1R1 2016/4885MEP1B 3459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.