Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894648 | 0.94 | RAB9A (0.55) | RAB9AALDH1A1HTTCNR2NPC1 | |
| SCHEMBL5435842 | 0.83 | ALDH1A1 (0.51) | RAB9AALDH1A1HTTSIGMAR1MCHR1 | |
| SCHEMBL20888587 | 0.83 | LMNA (0.62) | ALDH1A1HTTNUDT1TSHRLMNA | |
| SCHEMBL12002657 | 0.81 | MEN1 (0.48) | HDAC4HDAC6L3MBTL1NUDT1SIGMAR1 | |
| SCHEMBL12781811 | 0.81 | HDAC4 (0.47) | HTTHDAC4HDAC6NUDT1TSHR | |
| SCHEMBL15920640 | 0.79 | CA1 (0.45) | RAB9AALDH1A1HTTCNR2HDAC4 | |
| SCHEMBL7151264 | 0.79 | NPC1 (0.50) | RAB9AALDH1A1HTTCNR2NPC1 | |
| SCHEMBL5867321 | 0.78 | SLC2A1 (0.52) | RAB9AALDH1A1HTTNPC1MCHR1 | |
| SCHEMBL5971374 | 0.78 | CNR2 (0.55) | RAB9AALDH1A1HTTCNR2NPC1 | |
| SCHEMBL4452220 | 0.76 | RAB9A (0.49) | RAB9AALDH1A1HTTCNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295444-A2 | Lipopeptides as antibacterial agents | Cubist Pharmaceutical Inc. (US) | 2011-03-16 | — | — | EP | disclosed |