Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462525 | 0.82 | TDP1 (0.56) | RAB9AALDH1A1HTTCTBP2AOC3 | |
| SCHEMBL29894648 | 0.81 | RAB9A (0.55) | RAB9AALDH1A1HTTCNR2L3MBTL1 | |
| SCHEMBL4459739 | 0.79 | HTT (0.53) | RAB9AALDH1A1HTTL3MBTL1NPC1 | |
| SCHEMBL12809403 | 0.76 | RAB9A (0.50) | RAB9AALDH1A1HTTCNR2L3MBTL1 | |
| SCHEMBL5971374 | 0.76 | CNR2 (0.55) | RAB9AALDH1A1HTTCNR2L3MBTL1 | |
| SCHEMBL1707082 | 0.75 | RAB9A (0.51) | RAB9AALDH1A1HTTCNR2L3MBTL1 | |
| SCHEMBL15043962 | 0.75 | CYP2C19 (0.62) | RAB9AALDH1A1NPC1CYP2C9CYP2C19 | |
| SCHEMBL4958583 | 0.75 | ALDH1A1 (0.41) | RAB9AALDH1A1HTTL3MBTL1CYP2C9 | |
| SCHEMBL799654 | 0.74 | CA2 (0.64) | RAB9AALDH1A1L3MBTL1NPC1CYP2C9 | |
| 1,4-Dichlorobenzene SCHEMBL27657139 | 0.74 | TSHR (0.54) | RAB9AALDH1A1HTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | CONSEJO SUPERIOR DE (ES) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | BAX, BCL2, CASP3 | RAB9A 2249/4885ALDH1A1 1468/4885HTT 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.