Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605325 | 0.82 | KDM4E (0.58) | KDM4EPOLBATMKMT2AKCNA3 | |
| SCHEMBL19131301 | 0.82 | KDM4E (0.58) | KDM4EPOLBATMKMT2AKCNA3 | |
| Hydrochloric Acid SCHEMBL8584876 | 0.81 | KDM4E (0.56) | KDM4EPOLBATMKMT2AKCNA3 | |
| SCHEMBL11427052 | 0.81 | KDM4E (0.56) | KDM4EPOLBATMKMT2AKCNA3 | |
| SCHEMBL9796404 | 0.81 | KDM4E (0.56) | KDM4EPOLBATMKMT2AKCNA3 | |
| SCHEMBL11183506 | 0.78 | FEN1 (0.64) | KDM4EPOLBATMKMT2AKCNA3 | |
| SCHEMBL16523772 | 0.78 | KDM4E (0.62) | KDM4EPOLBATMKMT2AKCNA3 | |
| SCHEMBL8628627 | 0.77 | POLB (0.67) | KDM4EPOLBATMKMT2AALDH1A1 | |
| SCHEMBL6964053 | 0.75 | KDM4E (0.64) | KDM4EPOLBATMKMT2AKCNA3 | |
| SCHEMBL848499 | 0.75 | POLB (0.64) | KDM4EPOLBATMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298790-A1 | Daptomycin analogs as antibacterial agents | Cubist Pharmaceuticals, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| EP-2295444-A2 | Lipopeptides as antibacterial agents | Cubist Pharmaceutical Inc. (US) | 2011-03-16 | — | — | EP | disclosed |