(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL128109

C=C(C)C(=O)OC(C)N(C)C.ClCc1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
CHRNB2 P17787 2/20 0.36
CHRNB4 P30926 2/20 0.36
CHRNA3 P32297 2/20 0.36
CHRNA4 P43681 2/20 0.36
HPGD P15428 2/20 0.35
ELANE P08246 1/20 0.35
ALDH1A1 P00352 3/20 0.35
KCNH2 Q12809 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 2/20 0.34
TP53 P04637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
MRGPRX2 Q96LB1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL28986904 0.99 TSHR (0.38) TSHRCHRNB2CHRNB4CHRNA3CHRNA4
(Chloromethyl)Benzene SCHEMBL5930868 0.86 ADRA2A (0.39) TSHRHPGDELANEALDH1A1KCNH2
Benzylamine SCHEMBL27783614 0.86 LOXL2 (0.39) TSHRCHRNB2CHRNB4CHRNA3CHRNA4
Benzylamine SCHEMBL28102973 0.85 TSHR (0.38) TSHRCHRNB2CHRNB4CHRNA3CHRNA4
Dl-Phenylalanine SCHEMBL29214538 0.83 SLC7A5 (0.56)
(Chloromethyl)Benzene SCHEMBL169628 0.81 TSHR (0.39) TSHRCHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL28058991 0.80 HPGD (0.36) CHRNB2CHRNB4CHRNA3CHRNA4HPGD
Styrene SCHEMBL9002776 0.79 ALDH1A1 (0.40) TSHRHPGDELANEALDH1A1KCNH2
Chloromethane SCHEMBL127391 0.78 TSHR (0.41) TSHRALDH1A1
Acetic Acid SCHEMBL6065660 0.78 TSHR (0.41) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 919 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396410-A1 NOVEL COMPOSITION AND METHOD FOR PAPERMAKING ECOLAB USA INC. (US) 2024-07-10 EP claimed
US-20240218186-A1 METHOD OF PREPARING COATED PIGMENT AND WATER-BASED INK COMPOSITION CONTAINING COATED PIGMENT PREPARED THEREBY DONG-A PENCIL CO., LTD. (KR) 2024-07-04 US claimed
US-20240218187-A1 METHOD OF PREPARING COATED PIGMENT AND WATER-BASED INK COMPOSITION CONTAINING COATED PIGMENT PREPARED THEREBY DONG-A PENCIL CO., LTD. (KR) 2024-07-04 US claimed
EP-3825385-B1 DIAGNOSTIC DETERMINATION OF CLEANING PERFORMANCE BY USING FLUORESCENT POLYMERS IN MARKING COMPOSITIONS ECOLAB USA INC (US) 2024-06-12 EP claimed
US-11939309-B2 Low molecular weight dry powder polymer for use as paper-making dry strength agent ECOLAB USA INC. (US) 2024-03-26 US claimed
US-20240068168-A1 COMPOSITIONS AND METHODS FOR PAPERMAKING ECOLAB USA INC. (US) 2024-02-29 US claimed
US-20240052573-A1 STABLE CATIONIC POLYACRYLAMIDE DISPERSIONS AND USE THEREOF IN PAPERMAKING KEMIRA OYJ (FI) 2024-02-15 US claimed
US-20240010942-A1 OIL-IN-WATER EMULSIONS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-01-11 US claimed
US-11802220-B2 Silica-based slurry for selective polishing of carbon-based films CMC MATERIALS, INC. (US) 2023-10-31 US claimed
EP-4256009-A1 OIL-IN-WATER EMULSIONS Quadrise International Ltd (GB) 2023-10-11 EP claimed
US-6344531-B1 Fluorescent water-soluble polymers NALCO CHEMICAL COMPANY 2002-02-05 US claimed
WO-2001081654-A1 FLUORESCENT MONOMERS AND TAGGED TREATMENT POLYMERS CONTAINING SAME FOR USE IN INDUSTRIAL WATER SYSTEMS ONDEO NALCO COMPANY (US) 2001-11-01 WO claimed
WO-2000063023-A1 INKJET RECEPTOR MEDIUM HAVING A MULTI-STAGED INK MIGRATION INHIBITOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-10-26 WO claimed
EP-0872497-B1 Fluorescent cationic monomers useful for tagging water soluble polymers NALCO CHEMICAL CO (US) 2000-09-20 EP claimed
US-6103839-A Horizontally flowing continuous free radical polymerization process for manufacturing water-soluble polymers from monomers in aqueous solution NALCO CHEMICAL COMPANY (US) 2000-08-15 US claimed
US-6077461-A Cationic chemiluminescent monomers and polymers NALCO CHEMICAL COMPANY (US) 2000-06-20 US claimed
WO-2000018850-A1 CATIONIC CHEMILUMINESCENT MONOMERS AND POLYMERS NALCO CHEMICAL COMPANY (US) 2000-04-06 WO claimed
WO-1999058576-A1 HORIZONTALLY FLOWING CONTINUOUS FREE RADICAL POLYMERIZATION PROCESS FOR MANUFACTURING WATER-SOLUBLE POLYMERS FROM MONOMERS IN AQUEOUS SOLUTION NALCO CHEMICAL COMPANY (US) 1999-11-18 WO claimed
US-5986030-A CATIONIC POLYMERS FROM ACRYLIC DERIVATIVE MONOMERS AND COPOLYMERS NALCO CHEMICAL COMPANY (US) 1999-11-16 US claimed
EP-0872497-A2 Fluorescent cationic monomers useful for tagging water soluble polymers NALCO CHEMICAL COMPANY (US) 1998-10-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11939309-B2 Low molecular weight dry powder polymer for use as paper-making dry strength agent ACP1, PWWP2B, MACF1 TSHR 4478/4885CHRNB2 4222/4885CHRNB4 4075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.