Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 5/20 | 0.36 |
| ▸ | RARA | P10276 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813347 | 0.79 | ALDH1A1 (0.47) | RARBCYP1A2RARGRARARXRA | |
| SCHEMBL12813465 | 0.79 | RARB (0.43) | RARBCYP1A2RARGRARARXRA | |
| SCHEMBL8034537 | 0.78 | CYP1A2 (0.49) | TSHRRARBCYP1A2RARGRARA | |
| SCHEMBL12813381 | 0.77 | RARB (0.41) | RARBCYP1A2RARGRARARXRA | |
| SCHEMBL12813449 | 0.77 | RARB (0.41) | TSHRRARBCYP1A2RARGRARA | |
| SCHEMBL12813501 | 0.75 | HTT (0.45) | RARBCYP1A2RARGRARARXRA | |
| SCHEMBL12813413 | 0.74 | CES2 (0.40) | RARBCYP1A2RARGRARARXRA | |
| SCHEMBL12813293 | 0.74 | RARB (0.41) | TSHRRARBCYP1A2RARGRARA | |
| SCHEMBL12813484 | 0.74 | ALDH1A1 (0.42) | CYP1A2RXRARXRBRXRGKMT2A | |
| SCHEMBL16499388 | 0.74 | CYP1A2 (0.38) | RARBCYP1A2RARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |