Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | RARG | P13631 | 5/20 | 0.40 |
| ▸ | RARA | P10276 | 4/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813347 | 0.88 | ALDH1A1 (0.47) | RARBRARGRARASRD5A2HPGD | |
| SCHEMBL12813449 | 0.85 | RARB (0.41) | RARBRARGRARAMAPK1HPGD | |
| SCHEMBL12813465 | 0.84 | RARB (0.43) | RARBRARGRARARXRACYP1A2 | |
| SCHEMBL12813736 | 0.84 | TAS1R3 (0.40) | RARBRARGRARARXRA | |
| SCHEMBL12813534 | 0.83 | MEN1 (0.41) | RARBRARGRARAHPGDRXRA | |
| SCHEMBL12813293 | 0.82 | RARB (0.41) | RARBRARGRARAHPGDRXRA | |
| SCHEMBL12813339 | 0.81 | RARB (0.42) | RARBRARGRARARXRACES2 | |
| SCHEMBL12813472 | 0.81 | SRD5A2 (0.44) | RARBRARGRARASRD5A2HPGD | |
| SCHEMBL16499394 | 0.81 | RARB (0.47) | RARBRARGRARARXRA | |
| SCHEMBL12813501 | 0.81 | HTT (0.45) | RARBRARGRARARXRACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |