Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 5/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
| ▸ | RARG | P13631 | 6/20 | 0.39 |
| ▸ | RARA | P10276 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813534 | 0.87 | MEN1 (0.41) | RARBNPC1POLBRXRARXRB | |
| SCHEMBL12813462 | 0.85 | ALOX15 (0.44) | HTTRARBALDH1A1LMNARXRA | |
| SCHEMBL12813347 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2RARBALDH1A1MAPTLMNA | |
| SCHEMBL12813339 | 0.83 | RARB (0.42) | RARBRXRARXRBRXRGRARG | |
| SCHEMBL12813449 | 0.81 | RARB (0.41) | SMN1; SMN2RARBALDH1A1MAPTTDP1 | |
| SCHEMBL12813381 | 0.81 | RARB (0.41) | RARBTDP1RXRARARGRARA | |
| SCHEMBL12813465 | 0.80 | RARB (0.43) | RARBALDH1A1RXRARXRBRXRG | |
| SCHEMBL12813736 | 0.80 | TAS1R3 (0.40) | HTTSMN1; SMN2RARBALDH1A1MAPT | |
| SCHEMBL8034537 | 0.79 | CYP1A2 (0.49) | SMN1; SMN2RARBALDH1A1MAPTTDP1 | |
| SCHEMBL12813293 | 0.78 | RARB (0.41) | HTTSMN1; SMN2RARBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |