Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.41 |
| ▸ | RARG | P13631 | 6/20 | 0.40 |
| ▸ | RARA | P10276 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813347 | 0.88 | ALDH1A1 (0.47) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL12813381 | 0.85 | RARB (0.41) | RARBRARGRARAHPGDMAPK1 | |
| SCHEMBL12813465 | 0.84 | RARB (0.43) | RARBRARGRARAALDH1A1RXRA | |
| SCHEMBL12813472 | 0.84 | SRD5A2 (0.44) | RARBRARGRARAHPGDTSHR | |
| SCHEMBL12813339 | 0.84 | RARB (0.42) | RARBRARGRARARXRACYP1A2 | |
| SCHEMBL12813417 | 0.83 | CES2 (0.42) | RARBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL12813293 | 0.82 | RARB (0.41) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL16499394 | 0.81 | RARB (0.47) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL12813736 | 0.81 | TAS1R3 (0.40) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL12813157 | 0.81 | NPC1 (0.40) | RARBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |