Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813465 | 0.81 | RARB (0.43) | RXRARXRBRXRGCYP1A2RARB | |
| SCHEMBL8034537 | 0.80 | CYP1A2 (0.49) | RXRARXRBRXRGCYP1A2RARB | |
| SCHEMBL12813449 | 0.76 | RARB (0.41) | RXRARXRBRXRGCYP1A2NPC1 | |
| SCHEMBL12813347 | 0.75 | ALDH1A1 (0.47) | RXRACYP1A2NPC1RAB9ARARB | |
| SCHEMBL12813375 | 0.75 | CES2 (0.44) | HTTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL12813501 | 0.75 | HTT (0.45) | HTTRXRARXRBRXRGCYP1A2 | |
| SCHEMBL12813484 | 0.74 | ALDH1A1 (0.42) | HTTRXRARXRBRXRGCYP1A2 | |
| SCHEMBL12813710 | 0.73 | CYP1A2 (0.41) | RXRARXRBRXRGCYP1A2RARB | |
| SCHEMBL16499393 | 0.73 | HTT (0.40) | HTTP2RX7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12813381 | 0.73 | RARB (0.41) | RXRACYP1A2RARBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |