Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12816114 | 0.84 | CALM1 (0.33) | ALDH1A1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL12815488 | 0.80 | ALDH1A1 (0.31) | ALDH1A1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL12815381 | 0.80 | HPGD (0.33) | CALM1 | |
| Hydrochloric Acid SCHEMBL12816089 | 0.79 | ALDH1A1 (0.35) | ALDH1A1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL12817914 | 0.77 | RXRA (0.32) | — | |
| Hydrochloric Acid SCHEMBL12816365 | 0.77 | PDE4A (0.30) | — | |
| Hydrochloric Acid SCHEMBL12816452 | 0.76 | CALM1 (0.33) | ALDH1A1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL12816372 | 0.75 | RAB9A (0.37) | ALDH1A1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL12825804 | 0.74 | ALDH1A1 (0.35) | ALDH1A1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL12816197 | 0.73 | CALM1 (0.31) | CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012133936-A1 | CATALYST FOR PRODUCING ETHYLENE-BASED POLYMER AND METHOD FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012133919-A1 | PROCESS FOR PRODUCING CATALYST FOR PRODUCING ETHYLENIC POLYMER, CATALYST FOR PRODUCING ETHYLENIC POLYMER AND PROCESS FOR PRODUCING ETHYLENIC POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | WO | disclosed |