Itaconate

Itaconate

SCHEMBL128186

C=C(CC(=O)O)C(=O)O.C=CN1CCCC1=O.C=COC(C)=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL17687381 0.89 ALOX15 (0.47) ALOX15HSD17B10
SCHEMBL29127 0.86 BRD4 (0.33)
SCHEMBL11318608 0.86 BRD4 (0.33)
SCHEMBL1067025 0.86 BRD4 (0.33)
SCHEMBL1068142 0.86 BRD4 (0.33)
SCHEMBL5068820 0.86 BRD4 (0.33)
SCHEMBL27922209 0.84
Ethylene Glycol SCHEMBL28167207 0.83 LMNA (0.33)
SCHEMBL28167001 0.83 BRD4 (0.32)
Maleic Acid SCHEMBL7803465 0.82 BLM (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113038991-A Cosmetic composition with long-lasting skin beautifying effect LVMH研究公司 2021-06-25 CN claimed
EP-2269695-B1 Cosmetic compositions comprising a combination of a copolymer and at least one amphoteric polymer. BEIERSDORF AG (DE) 2016-12-21 EP claimed
WO-2016091937-A1 AQUEOUS COMPOSITION COMPRISING HESPERETIN L'OREAL (FR) 2016-06-16 WO claimed
US-20050207992-A1 Mousse-type/foamable styling agents containing pregelatinized, cross-linked starch derivatives BEIERSDORF AG (DE) 2005-09-22 US claimed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US claimed
CN-113038991-B Cosmetic composition with long-lasting skin beautifying effect LVMH研究公司 2023-10-10 CN disclosed
EP-4206236-A1 COMPOUNDS, THEIR SYNTHESIS AND COMPOSITIONS COMPRISING THE COMPOUNDS FOR ENHANCED DEPOSITION OF POLYMERS ONTO HAIR SURFACES Kao Corporation (JP) 2023-07-05 EP disclosed
US-20220016012-A1 COSMETIC MAKE-UP COMPOSITION WITH LONG-LASTING SKIN-PERFECTING EFFECT L V M H RECHERCHE (FR) 2022-01-20 US disclosed
EP-3140011-B2 AQUEOUS COSMETIC POWDER COMPOSITION KAO GERMANY GMBH (DE) 2022-01-19 EP disclosed
US-20210338563-A1 HAIR TREATMENT COMPOSITION KAO GERMANY GMBH (DE) 2021-11-04 US disclosed
US-20210338556-A1 SHINE ENHANCING SPRAY COMPOSITION KAO GERMANY GMBH (DE) 2021-11-04 US disclosed
US-11123271-B2 Aqueous cosmetic powder composition KAO GERMANY GMBH (DE) 2021-09-21 US disclosed
EP-1504747-A1 Cosmetic composition for hair comprising cetyl PEG/PPG-10/1 dimethicone and ceramide KPSS-Kao Professional Salon Services GmbH (DE) 2005-02-09 EP disclosed
EP-0893983-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-12-05 EP disclosed
EP-0756861-B1 Composition for dyeing of human hair KAO CORP (JP) 2001-11-28 EP disclosed
US-5951969-A DEFORMING HAIR WITH REDUCING AGENT AND RINSING; FIXING BY APPLYING OXIDIZING FORMULATION; APPLYING BRIGHTENING FORMULATION AND RINSING GOLDWELL GMBH (DE) 1999-09-14 US disclosed
US-5906916-A COMPOSITION COMPRISING IODIDE SALT, BUFFER, WATER SOLUBLE CELLULOSE BASED POLYMER, WATER CARRIER; EXHIBITS COLOR TRANSITION IN RESPONSE TO PEROXIDE INTEGRATED BIOMEDICAL TECHNOLOGY INC. (US) 1999-05-25 US disclosed
EP-0893983-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1999-02-03 EP disclosed
WO-1997038667-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1997-10-23 WO disclosed
EP-0756861-A2 Composition for dyeing of human hair Kao Corporation (JP) 1997-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220016012-A1 COSMETIC MAKE-UP COMPOSITION WITH LONG-LASTING SKIN-PERFECTING EFFECT CUTA, KRT18, MKI67 ALOX15 38/4885HSD17B10 389/4885
US-20210338556-A1 SHINE ENHANCING SPRAY COMPOSITION SUCLG1, CUTA, TPH1 ALOX15 305/4885HSD17B10 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.