Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.31 |
| ▸ | UGT2B17 | O75795 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498934 | 1.00 | HSP90AA1 (0.33) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL16499354 | 0.80 | TRPA1 (0.40) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL9418971 | 0.74 | ALDH1A1 (0.35) | TRPA1NR1H2NR1H3NOTUM | |
| SCHEMBL16499261 | 0.73 | SLC6A4 (0.39) | CYP3A4TRPA1NR1H2NR1H3 | |
| SCHEMBL12825605 | 0.73 | SLC6A4 (0.39) | CYP3A4TRPA1NR1H2NR1H3 | |
| SCHEMBL12825583 | 0.70 | GAA (0.33) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL12813386 | 0.66 | SIGMAR1 (0.44) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL12813226 | 0.64 | NR3C1 (0.43) | MEN1MAPK1KMT2AUGT2B7UGT2B17 | |
| SCHEMBL16499409 | 0.64 | HSP90AA1 (0.33) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL16499408 | 0.64 | HSP90AA1 (0.33) | HSP90AA1KDM4EMEN1USP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |