Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10299334 | 0.94 | MKNK1 (0.38) | RXFP1EIF4EMKNK1MKNK2SMO | |
| SCHEMBL10299320 | 0.93 | POLB (0.41) | KMT2AMEN1MAPK1POLBMAPT | |
| SCHEMBL10299318 | 0.88 | MKNK1 (0.36) | KMT2AMEN1EIF4EMKNK1MKNK2 | |
| SCHEMBL10003784 | 0.86 | HTR3A (0.45) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL10299336 | 0.85 | LMNA (0.35) | KMT2ASMOPOLBPTGDR2MAPT | |
| SCHEMBL10299326 | 0.85 | AHR (0.40) | POLBMAPTMETPDGFRBKIT | |
| SCHEMBL12020094 | 0.84 | SMO (0.36) | SMOPTGDR2MAPTMETNAMPT | |
| SCHEMBL10299353 | 0.83 | ALDH1A1 (0.42) | KMT2AMAPK1POLBNAMPTSMN1; SMN2 | |
| SCHEMBL10003727 | 0.83 | HKDC1 (0.37) | SMOPTGDR2SMN1; SMN2HKDC1KDM4E | |
| SCHEMBL10299362 | 0.82 | SRC (0.41) | SMOPOLBBRPF1PTGDR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024872-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |