Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181126 | 0.84 | ALDH1A1 (0.57) | ALOX5ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL9550474 | 0.82 | ALDH1A1 (0.47) | ALOX5ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL12075895 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTPKMHSD17B10HTT | |
| Hydrochloric Acid SCHEMBL15841782 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPTPKMHSD17B10HTT | |
| SCHEMBL7405206 | 0.75 | ALDH1A1 (0.65) | ALOX5ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL11361854 | 0.75 | ALDH1A1 (0.65) | ALOX5ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL9208149 | 0.74 | ALDH1A1 (0.69) | ALOX5ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL28429884 | 0.74 | ALDH1A1 (0.84) | ALOX5ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL14654432 | 0.72 | ALDH1A1 (0.76) | ALOX5ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL11705124 | 0.72 | ALDH1A1 (0.43) | ALOX5ALDH1A1MAPTPKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809104-A4 | METHODS FOR REGULATING NEUROTRANSMITTER SYSTEMS BY INDUCING COUNTERADAPTATIONS | MICHALOW ALEXANDER (US) | 2009-04-29 | — | — | EP | claimed |
| EP-2001495-A2 | METHODS FOR REGULATING NEUROTRANSMITTER SYSTEMS BY INDUCING COUNTERADAPTATIONS | Michalow, Alexander (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007100775-A2 | METHODS FOR REGULATING NEUROTRANSMITTER SYSTEMS BY INDUCING COUNTERADAPTATIONS | MICHALOW ALEXANDER (US) | 2007-09-07 | — | — | WO | claimed |
| EP-1809104-A2 | METHODS FOR REGULATING NEUROTRANSMITTER SYSTEMS BY INDUCING COUNTERADAPTATIONS | Michalow, Alexander (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2006034343-A2 | methods for regulating neurotransmitter systems by inducing counteradaptationS | MICHALOW ALEXANDER (US) | 2006-03-30 | — | — | WO | claimed |
| US-20060069086-A1 | Methods for regulating neurotransmitter systems by inducing counteradaptations | MICHALOW ALEXANDER | 2006-03-30 | — | — | US | claimed |
| US-6191126-B1 | TOPICAL ADMINISTERING | ALCON LABORATORIES, INC. | 2001-02-20 | — | — | US | claimed |
| WO-1997033580-A1 | MAINTAINING KIDNEY FUNCTION DURING SURGERY OR TRAUMA | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 1997-09-18 | — | — | WO | claimed |
| US-20250186427-A1 | METHODS AND COMPOSITIONS FOR TREATING VASOMOTOR SYMPTOMS | UNIVERSITY OF WASHINGTON | 2025-06-12 | — | — | US | disclosed |
| US-20240252484-A1 | Methods and Compositions for Treating Vasomotor Symptoms | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION | 2024-08-01 | — | — | US | disclosed |
| US-20240180895-A1 | USE OF KAPPA OPIOID RECEPTOR AGONISTS TO TREAT CARDIOVASCULAR DISEASE | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2024-06-06 | — | — | US | disclosed |
| US-20220125781-A1 | Methods and Compositions for Treating Vasomotor Symptoms | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION | 2022-04-28 | — | — | US | disclosed |
| US-11083726-B2 | Methods and compositions for treating vasomotor symptoms | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2021-08-10 | — | — | US | disclosed |
| US-20210030745-A9 | Methods and Compositions for Treating Vasomotor Symptoms | ACER THERAPEUTICS INC. | 2021-02-04 | — | — | US | disclosed |
| EP-2001495-A2 | METHODS FOR REGULATING NEUROTRANSMITTER SYSTEMS BY INDUCING COUNTERADAPTATIONS | Michalow, Alexander (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20080045610-A1 | Methods for regulating neurotransmitter systems by inducing counteradaptations | MICHALOW ALEXANDER | 2008-02-21 | — | — | US | disclosed |
| WO-2007100775-A2 | METHODS FOR REGULATING NEUROTRANSMITTER SYSTEMS BY INDUCING COUNTERADAPTATIONS | MICHALOW ALEXANDER (US) | 2007-09-07 | — | — | WO | disclosed |
| EP-1809104-A2 | METHODS FOR REGULATING NEUROTRANSMITTER SYSTEMS BY INDUCING COUNTERADAPTATIONS | Michalow, Alexander (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006034343-A2 | methods for regulating neurotransmitter systems by inducing counteradaptationS | MICHALOW ALEXANDER (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20060069086-A1 | Methods for regulating neurotransmitter systems by inducing counteradaptations | MICHALOW ALEXANDER | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030745-A9 | Methods and Compositions for Treating Vasomotor Symptoms | VASP, PDE3A, PDE2A | ALOX5 27/4885ALDH1A1 2052/4885MAPT 1530/4885 |
| US-20240252484-A1 | Methods and Compositions for Treating Vasomotor Symptoms | VASP, PDE3A, PDE2A | ALOX5 27/4885ALDH1A1 2052/4885MAPT 1530/4885 |
| US-20250186427-A1 | METHODS AND COMPOSITIONS FOR TREATING VASOMOTOR SYMPTOMS | VASP, PDE3A, PDE2A | ALOX5 27/4885ALDH1A1 2052/4885MAPT 1530/4885 |
| US-20080045610-A1 | Methods for regulating neurotransmitter systems by inducing counteradaptations | HTR5A, NTSR2, SLC6A2 | ALOX5 1481/4885ALDH1A1 1957/4885MAPT 1856/4885 |
| US-11083726-B2 | Methods and compositions for treating vasomotor symptoms | VASP, PDE3A, PDE2A | ALOX5 27/4885ALDH1A1 2052/4885MAPT 1530/4885 |
| US-20220125781-A1 | Methods and Compositions for Treating Vasomotor Symptoms | VASP, PDE3A, PDE2A | ALOX5 27/4885ALDH1A1 2052/4885MAPT 1530/4885 |
| US-20240180895-A1 | USE OF KAPPA OPIOID RECEPTOR AGONISTS TO TREAT CARDIOVASCULAR DISEASE | OPRK1, OPRL1, OPRM1 | ALOX5 1959/4885ALDH1A1 1077/4885MAPT 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.