Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181126 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL1282585 | 0.82 | ALOX5 (0.50) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL7405206 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL11361854 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL9208149 | 0.74 | ALDH1A1 (0.69) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL28429884 | 0.74 | ALDH1A1 (0.84) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL9867704 | 0.71 | ALDH1A1 (0.64) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL11705730 | 0.71 | ALDH1A1 (0.69) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL27649028 | 0.70 | SOS1 (0.57) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL11452978 | 0.69 | ALDH1A1 (0.60) | ALDH1A1MAPTPKMHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194465-A | — | — | None | — | — | JP | disclosed |
| JP-H05194465-A | 2-AMINO-MONO-METHOXYCYCLOHEXYLAMIDES USEFUL AS ANALGESIC | WARNER LAMBERT CO | 1993-08-03 | — | — | JP | disclosed |
| EP-0552386-A1 | 2-Amino-3 or 6-methoxycyclohexyl amide derivatives | WARNER-LAMBERT COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| US-5051428-A | 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics | WARNER-LAMBERT COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0372466-A2 | 2-Amino-4 or 5-methoxycyclohexyl amides useful as analgesics | WARNER-LAMBERT COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |