Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888556 | 0.89 | MAOA (0.32) | MAOAOPRD1OPRM1 | |
| SCHEMBL45987 | 0.80 | MAOA (0.31) | MAOAOPRD1OPRM1 | |
| SCHEMBL12831142 | 0.77 | OPRM1 (0.36) | OPRD1OPRM1 | |
| SCHEMBL13825005 | 0.77 | OPRM1 (0.36) | OPRD1OPRM1 | |
| SCHEMBL19322800 | 0.71 | OPRM1 (0.41) | OPRD1OPRM1 | |
| SCHEMBL13248810 | 0.67 | OPRM1 (0.37) | OPRD1OPRM1 | |
| SCHEMBL12091332 | 0.67 | OPRM1 (0.37) | OPRD1OPRM1 | |
| SCHEMBL10072372 | 0.67 | HCRTR1 (0.38) | OPRM1 | |
| SCHEMBL16541860 | 0.65 | OPRM1 (0.35) | OPRD1OPRM1 | |
| SCHEMBL21091551 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032214-A1 | A METHOD FOR THE N-DEMETHYLATION OF N-METHYL HETEROCYCLES | MONASH UNIVERSITY (AU) | 2011-03-24 | — | — | WO | disclosed |