Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12830845 | 0.80 | MAOA (0.33) | MAOAOPRM1OPRD1 | |
| SCHEMBL11888556 | 0.80 | MAOA (0.32) | MAOAOPRM1OPRD1OPRK1 | |
| SCHEMBL10072372 | 0.77 | HCRTR1 (0.38) | OPRM1OPRK1 | |
| SCHEMBL45963 | 0.77 | OPRM1 (0.35) | OPRM1OPRD1OPRK1 | |
| SCHEMBL45989 | 0.76 | — | — | |
| SCHEMBL19322756 | 0.71 | OPRM1 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL19322760 | 0.71 | OPRM1 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL17552962 | 0.71 | OPRM1 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL46027 | 0.67 | — | — | |
| SCHEMBL12337178 | 0.67 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005795-A1 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED MORPHINANS | ALKERMES, INC. (US) | 2012-01-12 | — | — | WO | disclosed |