Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CFTR | P13569 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341906 | 0.89 | HPGD (0.55) | NLRP3MEN1ABCC3ABCC4ABCC9 | |
| SCHEMBL3655826 | 0.84 | KCNA3 (0.52) | MEN1LMNAKMT2AFLT1FLT4 | |
| SCHEMBL29687002 | 0.84 | KCNA3 (0.52) | MEN1LMNAKMT2AFLT1FLT4 | |
| SCHEMBL120129 | 0.84 | KCNA3 (0.52) | MEN1LMNAKMT2AFLT1FLT4 | |
| SCHEMBL3304856 | 0.84 | FLT1 (0.67) | NLRP3MEN1LMNAKMT2AFLT1 | |
| SCHEMBL14303671 | 0.84 | FLT1 (0.59) | NLRP3MEN1ABCC3ABCC4ABCC9 | |
| SCHEMBL881108 | 0.84 | FLT1 (0.63) | NLRP3MEN1ABCC3ABCC4ABCC9 | |
| SCHEMBL14391687 | 0.83 | LMNA (0.67) | NLRP3LMNAFLT1FLT4KDR | |
| SCHEMBL14507295 | 0.80 | DNMT3A (0.56) | NLRP3MEN1ABCC3ABCC4ABCC9 | |
| SCHEMBL14507930 | 0.79 | ALDH1A1 (0.70) | NLRP3ALDH1A1LMNAFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920383-B2 | Active substances for increasing the stress defense in plants to abiotic stress, and methods of finding them | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-03-20 | — | — | US | disclosed |
| EP-2227458-B1 | Chiral 2-(Benzylsulfinyl)-thiazol derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]-thiazol derivatives with S-configuration as herbicide plant growth regulators | BAYER IP GMBH (DE) | 2016-06-22 | — | — | EP | disclosed |
| EP-2227457-B1 | CHIRAL 3-(BENZYLSULFINYL)-5,5-DIMETHYL-4,5-DIHYDROISOXAZOLE AND 5,5-DIMETHYL-3-[(1H-PYRAZOL-4-YLMETHYL) SULFINYL]-4,5-DIHYDROISOXAZOLE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-8901040-B2 | Active substances for increasing the stress defense in plants to abiotic stress, and methods of finding them | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-12-02 | — | — | US | disclosed |
| US-20140349849-A1 | Active Substances for Increasing the Stress Defense in Plants to Abiotic Stress, and Methods of Finding Them | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-11-27 | — | — | US | disclosed |
| US-8895471-B2 | Chiral3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1h-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihyddroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-11-25 | — | — | US | disclosed |
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-8420570-B2 | Chiral 3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1H-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihydroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulations | BAYER CROPSCIENCE AG (DE) | 2013-04-16 | — | — | US | disclosed |
| US-8420570-B2 | Chiral 3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole derivatives and 5,5-dimethyl-3-[(1H-pyrazol-4-ylmethyl)sulfinyl]-4,5-dihydroisoxazole derivatives, method for the production thereof, and use of same as herbicides and plant growth regulations | BAYER CROPSCIENCE AG (DE) | 2013-04-16 | — | — | US | disclosed |
| EP-2065373-A1 | Chiral 3-(benzylsulfinyl)-5,5-dimethyl-4,5-dihydroisoxazole and 5,5-dimethyl-3-[(1H-pyrazol-4-ylmethyl) sulfinyl]-4,5-dihydroisoxazole derivatives, methods for their preparation and their use as herbicides and plant growth regulators | Bayer CropScience AG (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065374-A1 | 2-(benzyl- and 1H-pyrazol-4-ylmethyl)sulfinyl-thiazol-derivatives as herbicides and plant growth regulators | Bayer CropScience AG (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2009018885-A1 | DIOXAZINYL-SUBSTITUTED FURYL-SULFONYL-AMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-02-12 | — | — | WO | disclosed |
| US-20070124839-A1 | Active substances for increasing the stress defense in plants to abiotic stress, and methods of finding them | BAYER CROPSCIENCE GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070015661-A1 | Herbicide/safener combination | BAYER CROPSCIENCE GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| WO-2007006409-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | WO | disclosed |
| US-20070015662-A1 | Herbicide/safener combination | BAYER CROPSCIENCE GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| WO-2007006416-A2 | CULTIGEN-COMPATIBLE HERBICIDAL AGENTS CONTAINING HERBICIDES AND ACYLSULFAMOYLBENZAMIDE SAFENERS | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | WO | disclosed |
| US-20070010399-A1 | Crop plant-compatible herbicidal compositions comprising herbicides and safeners | BAYER CROPSCIENCE GMBH (DE) | 2007-01-11 | — | — | US | disclosed |
| WO-2007003296-A1 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015662-A1 | Herbicide/safener combination | CYP2W1, CBR3, DDT | NLRP3 4288/4885MEN1 3038/4885ABCC3 221/4885 |
| US-20070015661-A1 | Herbicide/safener combination | CBR3, CBR1, GSR | NLRP3 4170/4885MEN1 3439/4885ABCC3 170/4885 |
| US-20070010399-A1 | Crop plant-compatible herbicidal compositions comprising herbicides and safeners | DDT, HACL2, CBR3 | NLRP3 4386/4885MEN1 4136/4885ABCC3 226/4885 |
| US-20140349849-A1 | Active Substances for Increasing the Stress Defense in Plants to Abiotic Stress, and Methods of Finding Them | HSF1, HSPA2, HSPA8 | NLRP3 3472/4885MEN1 4778/4885ABCC3 1883/4885 |
| US-20070124839-A1 | Active substances for increasing the stress defense in plants to abiotic stress, and methods of finding them | HSF1, HSPA2, HSPA8 | NLRP3 3472/4885MEN1 4778/4885ABCC3 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.