Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507531 | 0.75 | F10 (0.36) | — | |
| SCHEMBL12507710 | 0.74 | STS (0.41) | — | |
| SCHEMBL10280029 | 0.72 | CCR1 (0.39) | MEN1KMT2A | |
| SCHEMBL2942357 | 0.72 | SMYD3 (0.57) | SMYD3 | |
| SCHEMBL4095708 | 0.72 | SMYD3 (0.57) | SMYD3 | |
| SCHEMBL2942353 | 0.72 | SMYD3 (0.57) | SMYD3 | |
| SCHEMBL3256076 | 0.71 | PDE5A (0.41) | MEN1KMT2A | |
| SCHEMBL5563634 | 0.71 | PDE5A (0.41) | MEN1KMT2A | |
| SCHEMBL764562 | 0.71 | RAB9A (0.47) | SMYD3MEN1KMT2A | |
| SCHEMBL12507823 | 0.69 | FPR2 (0.33) | SMYD3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077266-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077266-A1 | Diamine Derivatives | F2, TFPI, F3 | SMYD3 2701/4885RIPK1 1728/4885MEN1 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.