Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764562 | 0.73 | RAB9A (0.47) | SMYD3POLBLMNAMAPT | |
| SCHEMBL1760636 | 0.71 | SIRT1 (0.44) | AADATAHRHDAC8MAPTGAA | |
| SCHEMBL12101100 | 0.71 | EPHX2 (0.36) | ROCK2GAA | |
| SCHEMBL3256484 | 0.70 | GAA (0.60) | AHRMAPTGAA | |
| SCHEMBL6246219 | 0.70 | GAA (0.60) | AHRMAPTGAA | |
| SCHEMBL6164822 | 0.70 | GAA (0.60) | AHRMAPTGAA | |
| SCHEMBL14641138 | 0.70 | PYGL (0.57) | MAPTGAA | |
| SCHEMBL12507531 | 0.69 | F10 (0.36) | — | |
| SCHEMBL12833317 | 0.69 | SMYD3 (0.32) | SMYD3ROCK2 | |
| SCHEMBL13889887 | 0.69 | GAA (0.42) | AHRHDAC8MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343290-A1 | Diamine derivatives as factor X inhibitors | Daiichi Sankyo Company, Limited (JP) | 2011-07-13 | — | — | EP | disclosed |