Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.49 |
| ▸ | THRA | P10827 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846204 | 0.86 | FFAR1 (0.61) | FFAR1THRATHRBFFAR4NPSR1 | |
| SCHEMBL1249170 | 0.86 | KEAP1 (0.52) | FFAR1THRATHRBFFAR4NPSR1 | |
| SCHEMBL10752951 | 0.85 | ALDH1A1 (0.46) | FFAR1THRATHRBFFAR4 | |
| SCHEMBL1246654 | 0.81 | THRB (0.43) | THRATHRB | |
| SCHEMBL14143792 | 0.79 | FFAR1 (0.50) | FFAR1THRATHRBFFAR4NPSR1 | |
| SCHEMBL26999653 | 0.78 | MCL1 (0.43) | FFAR1THRATHRBFFAR4PPARG | |
| SCHEMBL22088079 | 0.78 | FFAR1 (0.49) | FFAR1THRATHRBFFAR4NPSR1 | |
| SCHEMBL17705230 | 0.78 | THRA (0.50) | FFAR1THRATHRBFFAR4NPSR1 | |
| SCHEMBL3930469 | 0.78 | FFAR4 (0.47) | FFAR1THRATHRBFFAR4GPR17 | |
| SCHEMBL13180741 | 0.76 | CNR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292592-A1 | SULFONAMIDE COMPOUND AND APPLICATION THEREOF | Asahi Kasei Pharma Corporation (JP) | 2011-03-09 | — | — | EP | disclosed |