Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | BRCA1 | P38398 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.69 |
| ▸ | F2 | P00734 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentamidine SCHEMBL33615 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Hexamidine SCHEMBL985947 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL27719324 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL19462606 | 0.99 | ALDH1A1 (0.97) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL5014184 | 0.99 | ALDH1A1 (0.97) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL2658011 | 0.97 | ALDH1A1 (0.95) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL23063972 | 0.96 | ALDH1A1 (0.92) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Propamidine SCHEMBL293021 | 0.96 | ALDH1A1 (0.92) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL16050177 | 0.94 | ALDH1A1 (0.88) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| Pentamidine SCHEMBL18007221 | 0.94 | ALDH1A1 (0.88) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12433872-B2 | Treatment of Acanthamoeba or Balamuthia trophozoites and/or cysts | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2025-10-07 | — | — | US | claimed |
| WO-2024127414-A1 | A COSMETIC COMPOSITION FOR ACNE CONTROL AND METHODS THEREOF | L'OREAL (FR) | 2024-06-20 | — | — | WO | claimed |
| US-20230218641-A1 | ANTI-ACNE COMPOSITIONS | L'OREAL (FR) | 2023-07-13 | — | — | US | claimed |
| CN-115916147-A | Anti-acne composition | 欧莱雅 | 2023-04-04 | — | — | CN | claimed |
| EP-4153127-A1 | ANTI-ACNE COMPOSITIONS | L'OREAL (FR) | 2023-03-29 | — | — | EP | claimed |
| CN-115054539-A | Preparation process of gel for diminishing inflammation and removing scars | 湖南科洛克医药有限公司 | 2022-09-16 | — | — | CN | claimed |
| US-20220096441-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-03-31 | — | — | US | claimed |
| WO-2021234014-A1 | ANTI-ACNE COMPOSITIONS | L'OREAL (FR) | 2021-11-25 | — | — | WO | claimed |
| CN-111973499-A | Agent combination for skin care | 西安博和医疗科技有限公司 | 2020-11-24 | — | — | CN | claimed |
| WO-2020081829-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-04-23 | — | — | WO | claimed |
| US-20040167479-A1 | Hemorrhoid treatment pad | THE PROCTER & GAMBLE COMPANY | 2004-08-26 | — | — | US | claimed |
| US-20030078172-A1 | Foaming cosmetic cream | L'OREAL (FR) | 2003-04-24 | — | — | US | claimed |
| CN-1404821-A | Foaming cosmetic paste | OREAL (FR) | 2003-03-26 | — | — | CN | claimed |
| US-20020028222-A1 | Use of fibers in a care composition or a make-up composition to make the skin matte | L'OREAL (FR) | 2002-03-07 | — | — | US | claimed |
| EP-0652774-B1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER | PROCTER & GAMBLE (US) | 1997-05-07 | — | — | EP | claimed |
| US-5614178-A | TRANSDERMAL | THE PROCTER & GAMBLE COMPANY (US) | 1997-03-25 | — | — | US | claimed |
| US-5093109-A | For retarding effects of aging, anti-free radical ingredient, sunscreen agent, emulsion | CHANEL, INC. (US) | 1992-03-03 | — | — | US | claimed |
| EP-0093186-B1 | PHARMACEUTICAL PREPARATION FOR THE TOPICAL TREATMENT OF ACNE | RICHARDSON VICKS LIMITED (GB) | 1986-07-09 | — | — | EP | claimed |
| US-4505924-A | IMAZILIL AND HEXAMIDINE ISETHIONATE | RICHARDSON-VICKS LTD. (GB) | 1985-03-19 | — | — | US | claimed |
| EP-0093186-A1 | Pharmaceutical preparation for the topical treatment of acne | RICHARDSON VICKS LIMITED (GB) | 1983-11-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12433872-B2 | Treatment of Acanthamoeba or Balamuthia trophozoites and/or cysts | PKD2, PKD1, MUC1 | ALDH1A1 3071/4885LMNA 3130/4885POLB 895/4885 |
| US-20230218641-A1 | ANTI-ACNE COMPOSITIONS | CUTA, EBP, ACMSD | ALDH1A1 819/4885LMNA 2543/4885POLB 182/4885 |
| US-20220096441-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | PKD2, PKD1, MUC1 | ALDH1A1 3071/4885LMNA 3130/4885POLB 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.