Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12777084 | 0.92 | NPC1 (0.38) | NPC1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12380352 | 0.85 | ALDH1A1 (0.45) | NPC1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL2296437 | 0.85 | KDM4E (0.51) | NPC1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12777044 | 0.84 | MET (0.50) | NPC1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12777037 | 0.84 | NPC1 (0.47) | NPC1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12844652 | 0.83 | NPC1 (0.42) | NPC1RAB9AHDAC6HSPD1PTPN2 | |
| SCHEMBL12776893 | 0.82 | HPGD (0.45) | NPC1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12776908 | 0.80 | ALDH1A1 (0.58) | NPC1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL13170865 | 0.80 | METAP2 (0.40) | KDM4EALDH1A1SMN1; SMN2TSHRATM | |
| SCHEMBL15446817 | 0.80 | ALDH1A1 (0.52) | NPC1KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7901794-B2 | Material for light-emitting element and light emitting element | TORAY INDUSTRIES, INC. (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20090066245-A1 | MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT | TORAY INDUSTRIES, INC. (JP) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090066245-A1 | MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT | PYM1, CRY1, S100A10 | NPC1 2742/4885KDM4E 1639/4885ALDH1A1 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.