Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | RGS12 | O14924 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443285 | 0.91 | TTR (0.52) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10493540 | 0.86 | NFKB1 (0.45) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL17655654 | 0.86 | TTR (0.47) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL9244309 | 0.84 | TTR (0.45) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL1175107 | 0.84 | EGFR (0.54) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL8440705 | 0.82 | MEN1 (0.64) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL1175171 | 0.82 | CYP19A1 (0.47) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL17744575 | 0.82 | TTR (0.44) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4168959 | 0.79 | MEN1 (0.56) | EGFRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL6302783 | 0.79 | PTGS2 (0.50) | EGFRLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299276-B2 | Interlocked molecules and related components, compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-10-30 | — | — | US | disclosed |
| US-20110065935-A1 | INTERLOCKED MOLECULES AND RELATED COMPONENTS, COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065935-A1 | INTERLOCKED MOLECULES AND RELATED COMPONENTS, COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS | ECPAS, RAD52, ILK | EGFR 4122/4885LMNA 800/4885MEN1 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.