Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | TTR | P02766 | 2/20 | 0.64 |
| ▸ | ALB | P02768 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.44 |
| ▸ | PTP4A2 | Q12974 | 2/20 | 0.44 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443285 | 0.86 | TTR (0.52) | MEN1KMT2ATTRALBALOX5 | |
| SCHEMBL12846356 | 0.82 | EGFR (0.51) | MEN1KMT2ATTRALBALOX5 | |
| SCHEMBL17655654 | 0.81 | TTR (0.47) | MEN1KMT2ATTRALBALOX5 | |
| Bromoxynil SCHEMBL1701902 | 0.80 | TTR (1.00) | MEN1KMT2ATTRALBEGFR | |
| Bromoxynil SCHEMBL19210 | 0.80 | TTR (1.00) | MEN1KMT2ATTRALBEGFR | |
| SCHEMBL1175107 | 0.79 | EGFR (0.54) | MEN1KMT2ATTRALBALOX5 | |
| SCHEMBL9244309 | 0.79 | TTR (0.45) | MEN1KMT2ATTRALBALOX5 | |
| SCHEMBL523635 | 0.79 | TSHR (0.46) | MEN1KMT2ATTRALBALOX15 | |
| SCHEMBL1614422 | 0.78 | AR (0.43) | MEN1KMT2ATTRALBEGFR | |
| SCHEMBL1175171 | 0.78 | CYP19A1 (0.47) | MEN1KMT2ATTRALBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344604-B1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-11-04 | — | — | EP | disclosed |
| CN-106478500-B | Carboxylic acid substituted (hetero) aromatic ring derivatives, and preparation method and application thereof | 广东东阳光药业有限公司 | 2020-02-11 | — | — | CN | disclosed |
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-04-23 | — | — | US | disclosed |
| EP-3344604-A1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-11 | — | — | EP | disclosed |
| US-20170223964-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | BASF SE (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20170181435-A1 | Combination of Novel Nitrification Inhibitors and Biopesticides as Well as Combination of (Thio)Phosphoric Acid Triamides and Biopesticides | BASF SE (DE) | 2017-06-29 | — | — | US | disclosed |
| WO-2017036404-A1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-09 | — | — | WO | disclosed |
| US-20170036969-A1 | NITRIFICATION INHIBITORS | BASF SE (DE) | 2017-02-09 | — | — | US | disclosed |
| CN-1060159-C | Preparation for aromatic nitrile compound | CIBA GEIGY (CH) | 2001-01-03 | — | — | CN | disclosed |
| EP-0731086-B1 | Process for the preparation of aromatic nitriles | CIBA GEIGY AG (CH) | 1999-04-28 | — | — | EP | disclosed |
| US-5618965-A | Process for preparing aromatic nitriles | CIBA-GEIGY CORPORATION (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0731086-A1 | Process for the preparation of aromatic nitriles | CIBA-GEIGY AG (CH) | 1996-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036969-A1 | NITRIFICATION INHIBITORS | NOS1, NOS2, NOS3 | MEN1 4434/4885KMT2A 1097/4885TTR 4155/4885 |
| US-20170181435-A1 | Combination of Novel Nitrification Inhibitors and Biopesticides as Well as Combination of (Thio)Phosphoric Acid Triamides and Biopesticides | PRXL2A, NIT2, NAT1 | MEN1 4441/4885KMT2A 3605/4885TTR 626/4885 |
| US-20170223964-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | NAT1, PRXL2A, DDAH1 | MEN1 4652/4885KMT2A 2199/4885TTR 935/4885 |
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | XDH, ABCG2, SLC7A1 | MEN1 4506/4885KMT2A 3821/4885TTR 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.