SCHEMBL12847792

SCHEMBL12847792

CC(=Cc1ccc(N(c2ccc(C)cc2)c2c3ccccc3cc3ccccc23)cc1)C(=O)c1ccccc1C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.36
MAPT P10636 4/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 4/20 0.32
MEN1 O00255 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
AKR1C3 P42330 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12848233 0.81 TRPM8 (0.42) TUBB1TRPM8MAPTNPC1RAB9A
SCHEMBL12848023 0.77 TUBB1 (0.36) TUBB1TRPM8KMT2AMEN1
SCHEMBL3284757 0.75 CYP1A2 (0.44) NPSR1KDM4EALDH1A1GAA
SCHEMBL12084938 0.74 MAPT (0.47) TRPM8MAPTNPC1RAB9AKMT2A
SCHEMBL10165513 0.73 CYP1A2 (0.35) TRPM8MAPTRAB9ANPSR1KDM4E
SCHEMBL14003983 0.72 CYP1A2 (0.41) MAPTNPSR1KDM4EKMT2AMEN1
SCHEMBL4865622 0.72 AKR1C3 (0.58) TRPM8MAPTNPC1RAB9AKDM4E
SCHEMBL12744271 0.71 CYP1A2 (0.40) MAPTNPC1RAB9ANPSR1KDM4E
SCHEMBL12998359 0.71 TUBB1 (0.38) TUBB1MAPTNPSR1KDM4EKMT2A
SCHEMBL36539 0.71 CYP1A2 (0.42) NPC1RAB9ANPSR1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO TUBB1 2461/4885TRPM8 3852/4885MAPT 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.