Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Loliolide SCHEMBL789415 | 0.71 | ACHE (0.53) | ACHE | |
| Loliolide SCHEMBL10181773 | 0.71 | ACHE (0.53) | ACHE | |
| Loliolide SCHEMBL16057196 | 0.71 | ACHE (0.53) | ACHE | |
| SCHEMBL15507620 | 0.67 | PTPN1 (0.34) | LMNANPC1GMNNMTORRAB9A | |
| SCHEMBL8378487 | 0.65 | ENO1 (0.32) | — | |
| SCHEMBL8165368 | 0.65 | ENO1 (0.32) | — | |
| SCHEMBL7838483 | 0.65 | ENO1 (0.32) | — | |
| SCHEMBL8677887 | 0.65 | ENO1 (0.32) | — | |
| SCHEMBL5713354 | 0.65 | ENO1 (0.32) | — | |
| SCHEMBL6720724 | 0.65 | ENO1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902384-B2 | Estrogenic-active compounds and application thereof | NATIONAL TAIWAN UNIVERSITY (TW) | 2011-03-08 | — | — | US | disclosed |