Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | OGT | O15294 | 1/20 | 0.52 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.46 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460679 | 0.79 | OGT (0.47) | MAOAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL21564027 | 0.77 | MAOA (0.48) | MAOAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL12849525 | 0.76 | ALDH1A1 (0.61) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL8691721 | 0.74 | ERCC5 (0.54) | MAOAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL29357643 | 0.74 | GABRP (0.58) | MAOAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL29520332 | 0.74 | GABRP (0.58) | MAOAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12105369 | 0.74 | GABRP (0.58) | MAOAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL2002523 | 0.72 | KDM4E (0.52) | MAOAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL17433180 | 0.72 | KIF11 (0.53) | MAOAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL16925770 | 0.72 | CDK5 (0.58) | KDM4EALDH1A1GLAMAPTMAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034051-A1 | NOVEL CYCLIC SQUARAMIDE DERIVATIVES | 参天製薬株式会社 (JP) | 2011-03-24 | — | — | WO | disclosed |