Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 8/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9991690 | 0.95 | TRPV1 (0.54) | TRPV1ARJAK2TP53MAPT | |
| SCHEMBL8134750 | 0.81 | AR (0.51) | ARJAK2TP53MAPTHTT | |
| SCHEMBL1405006 | 0.79 | ALDH1A1 (0.51) | ARJAK2TP53MAPTHTT | |
| SCHEMBL6969 | 0.78 | AR (0.51) | ARJAK2TP53MAPTHTT | |
| SCHEMBL4689879 | 0.76 | SLC16A3 (0.50) | TRPV1SLC16A3 | |
| SCHEMBL14333034 | 0.75 | TDP1 (0.44) | TRPV1SLC16A3 | |
| SCHEMBL8709315 | 0.74 | AR (0.44) | TRPV1ARJAK2TP53MAPT | |
| SCHEMBL8419387 | 0.74 | ALDH1A1 (0.50) | TRPV1HTTSLC16A3 | |
| SCHEMBL10649798 | 0.74 | AR (0.48) | ARJAK2TP53MAPTHTT | |
| SCHEMBL6934824 | 0.74 | SLC16A3 (0.41) | TRPV1MAPTSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012126084-A1 | HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE IΝ THE TREATMENT AND PREVENTION OF FUNGAL INFECTIONS | PHARMASCIENCE INC. (CA) | 2012-09-27 | — | — | WO | disclosed |