Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646923 | 0.85 | CA1 (0.47) | ARCFTRGAAHTTPDK1 | |
| SCHEMBL10652081 | 0.83 | CA1 (0.54) | CFTRPDK1PDK2PDK3PDK4 | |
| SCHEMBL8513330 | 0.79 | ALDH1A1 (0.50) | CFTRHTTLMNAMAPK1ALDH1A1 | |
| SCHEMBL6969 | 0.79 | AR (0.51) | ARHTTMAPTTP53JAK2 | |
| SCHEMBL8134750 | 0.79 | AR (0.51) | ARHTTMAPTTP53JAK2 | |
| SCHEMBL7934022 | 0.76 | CFTR (0.51) | CFTRGAAHTTMAPTMEN1 | |
| SCHEMBL4344024 | 0.76 | PDK1 (0.70) | GAAHTTMAPTTP53JAK2 | |
| SCHEMBL9991690 | 0.75 | TRPV1 (0.54) | ARHTTMAPTTP53JAK2 | |
| SCHEMBL1405006 | 0.74 | ALDH1A1 (0.51) | ARGAAHTTMAPTTP53 | |
| SCHEMBL12849679 | 0.74 | TRPV1 (0.50) | ARHTTMAPTTP53JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764623-A | N-(1H-tetrazol-5-yl-alkylphenyl)polyfluoroalkanamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |