Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | IAPP | P10997 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404979 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNAIAPPHTTPOLB | |
| SCHEMBL8134750 | 0.81 | AR (0.51) | ALDH1A1ARJAK2TP53MAPT | |
| SCHEMBL27778032 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAIAPPHTTPOLB | |
| SCHEMBL9991690 | 0.80 | TRPV1 (0.54) | ALDH1A1ARJAK2TP53MAPT | |
| SCHEMBL12849679 | 0.79 | TRPV1 (0.50) | ARJAK2TP53MAPTHTT | |
| SCHEMBL6969 | 0.78 | AR (0.51) | ALDH1A1ARJAK2TP53MAPT | |
| SCHEMBL1405181 | 0.77 | AR (0.41) | ALDH1A1ARJAK2TP53MAPT | |
| SCHEMBL3600530 | 0.75 | L3MBTL1 (0.59) | ALDH1A1JAK2TP53MAPTHTT | |
| SCHEMBL8709315 | 0.74 | AR (0.44) | ARJAK2TP53MAPTHTT | |
| SCHEMBL1405115 | 0.74 | ALDH1A1 (0.53) | ALDH1A1LMNAIAPPMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079747-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LTD (GB) | 2011-03-09 | — | — | EP | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161288-A1 | COMPOUNDS | ADRB2, ADRB1, ADRA2C | ALDH1A1 295/4885LMNA 1543/4885AR 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.