Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849679 | 0.95 | TRPV1 (0.50) | TRPV1ARJAK2TP53MAPT | |
| SCHEMBL8134750 | 0.82 | AR (0.51) | ARJAK2TP53MAPTHTT | |
| SCHEMBL4689879 | 0.80 | SLC16A3 (0.50) | TRPV1SLC16A3HDAC1HDAC7HDAC8 | |
| SCHEMBL1405006 | 0.80 | ALDH1A1 (0.51) | ARJAK2TP53MAPTHTT | |
| SCHEMBL8419387 | 0.79 | ALDH1A1 (0.50) | TRPV1HTTSLC16A3HDAC1HDAC7 | |
| SCHEMBL6969 | 0.79 | AR (0.51) | ARJAK2TP53MAPTHTT | |
| SCHEMBL8709315 | 0.76 | AR (0.44) | TRPV1ARJAK2TP53MAPT | |
| SCHEMBL20856584 | 0.75 | TGM2 (0.46) | TRPV1SLC16A3ALDH1A1HPGD | |
| SCHEMBL10649798 | 0.75 | AR (0.48) | ARJAK2TP53MAPTHTT | |
| SCHEMBL4691306 | 0.75 | TRPV1 (0.46) | TRPV1SLC16A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778948-B2 | Substituted phenylpiperazinyl aralkylalcohol derivatives, pharmaceutical compositions containing such derivatives and uses thereof | NHWA Pharma, Corporation (CN) | 2014-07-15 | — | — | US | disclosed |
| US-20110294822-A1 | Substituted Phenylpiperazinyl Aralkylalcohol Derivatives, Pharmaceutical Compositions Containing Such Derivatives and Uses Thereof | NHWA PHARMA. CORPORATION (CN) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294822-A1 | Substituted Phenylpiperazinyl Aralkylalcohol Derivatives, Pharmaceutical Compositions Containing Such Derivatives and Uses Thereof | OPRL1, OPRK1, OPRD1 | TRPV1 24/4885AR 29/4885JAK2 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.