Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398764 | 0.86 | ALDH1A1 (0.42) | RAPGEF4IDO1EGFRALDH1A1CYP1A2 | |
| SCHEMBL3793129 | 0.86 | EGFR (0.40) | RAPGEF4EGFRALDH1A1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL3396163 | 0.84 | ALDH1A1 (0.41) | RAPGEF4IDO1EGFRALDH1A1CYP1A2 | |
| SCHEMBL5280349 | 0.84 | THRB (0.50) | RAPGEF4THRBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11528767 | 0.78 | THRB (0.52) | RAPGEF4THRBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3787936 | 0.77 | CYP3A4 (0.48) | RAPGEF4IDO1EGFRALDH1A1CYP1A2 | |
| SCHEMBL20620250 | 0.77 | RAPGEF4 (0.49) | RAPGEF4IDO1TDO2EGFRALDH1A1 | |
| SCHEMBL17546644 | 0.75 | THRA (0.40) | RAPGEF4THRBALDH1A1MAPTKDM4E | |
| SCHEMBL16786088 | 0.75 | RAPGEF4 (0.48) | RAPGEF4IDO1TDO2ALDH1A1MAPT | |
| SCHEMBL12136032 | 0.74 | RAPGEF4 (0.44) | RAPGEF4THRBCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |
| US-8278455-B2 | 5- or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-10-02 | — | — | US | disclosed |