Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127982 | 0.83 | HCAR2 (0.48) | HCAR2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL128626 | 0.82 | TSHR (0.59) | ALDH1A1TSHRHSD17B10MAPTALOX15 | |
| SCHEMBL8565583 | 0.79 | CHRNB2 (0.43) | HCAR2NPSR1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL127528 | 0.79 | ATM (0.59) | HCAR2NPSR1ALDH1A1TSHRMAPT | |
| SCHEMBL1126891 | 0.78 | HCAR2 (0.52) | HCAR2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL6673309 | 0.78 | HCAR2 (0.52) | HCAR2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL28541 | 0.78 | HCAR2 (0.52) | HCAR2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL127141 | 0.78 | HCAR2 (0.42) | HCAR2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL125807 | 0.76 | — | — | |
| SCHEMBL128754 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504210-B1 | 7-SUBSTITUTED SULFONIMIDOYLPURINONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2021-02-24 | — | — | EP | claimed |
| US-20080064873-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-13 | — | — | US | claimed |
| US-5753671-A | Imidazopyridine derivatives as dual histamine (H1) and platelet activating factor (PAF) antagonists | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-05-19 | — | — | US | claimed |
| EP-0775139-A1 | IMIDAZOPYRIDINE DERIVATIVES AS DUAL HISTAMINE (H1) AND PLATELET ACTIVATING FACTOR (PAF) ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-05-28 | — | — | EP | claimed |
| WO-1996005201-A1 | IMIDAZOPYRIDINE DERIVATIVES AS DUAL HISTAMINE (H1) AND PLATELET ACTIVATING FACTOR (PAF) ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-02-22 | — | — | WO | claimed |
| CN-112930499-B | Electrophotographic photoreceptor | 京瓷办公信息系统株式会社 | 2023-12-29 | — | — | CN | disclosed |
| CN-107148423-B | Thionucleoside derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2021-07-30 | — | — | CN | disclosed |
| CN-108700838-B | Electrophotographic photoreceptor | 京瓷办公信息系统株式会社 | 2021-07-16 | — | — | CN | disclosed |
| CN-112930499-A | Electrophotographic photoreceptor | 京瓷办公信息系统株式会社 | 2021-06-08 | — | — | CN | disclosed |
| WO-2020084900-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY | 京セラドキュメントソリューションズ株式会社 | 2020-04-30 | — | — | WO | disclosed |
| CN-111051995-A | Electrophotographic photoreceptor | 京瓷办公信息系统株式会社 | 2020-04-21 | — | — | CN | disclosed |
| US-10338485-B2 | Electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-07-02 | — | — | US | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-5753671-A | Imidazopyridine derivatives as dual histamine (H1) and platelet activating factor (PAF) antagonists | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| EP-0775139-A1 | IMIDAZOPYRIDINE DERIVATIVES AS DUAL HISTAMINE (H1) AND PLATELET ACTIVATING FACTOR (PAF) ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005201-A1 | IMIDAZOPYRIDINE DERIVATIVES AS DUAL HISTAMINE (H1) AND PLATELET ACTIVATING FACTOR (PAF) ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064873-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | REN, CMA1, AKR1A1 | HCAR2 691/4885NPSR1 778/4885ALDH1A1 160/4885 |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | HCAR2 99/4885NPSR1 859/4885ALDH1A1 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.