Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12270345 | 0.85 | — | — | |
| SCHEMBL12859617 | 0.69 | GPR3 (0.42) | CHEK1CDK5CDK5R1 | |
| SCHEMBL19683284 | 0.66 | CYP3A4 (0.32) | — | |
| SCHEMBL15372465 | 0.66 | PTPN1 (0.35) | — | |
| SCHEMBL12270343 | 0.66 | KDM5A (0.36) | CHEK1CDK5CDK5R1 | |
| SCHEMBL13169664 | 0.63 | PTPN1 (0.34) | — | |
| SCHEMBL12859619 | 0.63 | HTR1A (0.33) | — | |
| SCHEMBL12270320 | 0.63 | PTPN2 (0.35) | CHEK1CDK5CDK5R1 | |
| SCHEMBL19683276 | 0.62 | CYP3A4 (0.33) | — | |
| SCHEMBL19683285 | 0.62 | CYP1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | KEIO UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | KEIO UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | AHR, AR, ARNT | CHEK1 3000/4885CDK5 2660/4885CDK5R1 2112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.