Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12270317 | 0.86 | KDM4E (0.34) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL12270385 | 0.76 | HTR1A (0.39) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL12859617 | 0.70 | GPR3 (0.42) | — | |
| SCHEMBL12270179 | 0.67 | GPR3 (0.39) | — | |
| SCHEMBL12270275 | 0.64 | DYRK1A (0.38) | — | |
| SCHEMBL13169665 | 0.63 | KDM4E (0.36) | HTR1AHTR2C | |
| SCHEMBL12859618 | 0.63 | CHEK1 (0.31) | — | |
| SCHEMBL20213576 | 0.62 | DYRK1A (0.37) | — | |
| SCHEMBL17072186 | 0.62 | DYRK1A (0.37) | — | |
| SCHEMBL12270507 | 0.62 | CHEK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | KEIO UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | KEIO UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | AHR, AR, ARNT | HTR1A 118/4885HTR2C 203/4885HTR3E 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.