Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960866 | 0.85 | TP53 (0.50) | PTGS2ALDH1A1CYP3A4CYP2C19MAPT | |
| SCHEMBL15928819 | 0.83 | PTGS2 (0.39) | PTGS2MAOBALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL6666505 | 0.78 | LMNA (0.50) | MAOBALDH1A1CYP2C19MAPTLMNA | |
| SCHEMBL4213663 | 0.78 | LMNA (0.46) | MAOBALDH1A1CYP2C19MAPTKMT2A | |
| SCHEMBL3536597 | 0.78 | PTGS2 (0.41) | PTGS2ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL3145722 | 0.77 | LMNA (0.46) | MAOBALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4128241 | 0.77 | IDO1 (0.53) | CYP2D6 | |
| SCHEMBL27805567 | 0.77 | ALDH1A1 (0.37) | PTGS2MAOBALDH1A1MAPTKMT2A | |
| SCHEMBL678302 | 0.76 | PTGS2 (0.62) | PTGS2ALDH1A1CYP3A4MAPTKMT2A | |
| SCHEMBL15267352 | 0.75 | ALDH1A1 (0.55) | MAOBALDH1A1CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486974-B2 | Efficient aspirin prodrugs | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH (IE) | 2013-07-16 | — | — | US | disclosed |
| US-20110046182-A1 | EFFICIENT ASPIRIN PRODRUGS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABE (IE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046182-A1 | EFFICIENT ASPIRIN PRODRUGS | COX15, PTGS1, CYP3A43 | PTGS2 6/4885MAOB 1084/4885ALDH1A1 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.