SCHEMBL1286664

SCHEMBL1286664

CC(=O)c1ccc(CO)cc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.70
LMNA P02545 2/20 0.59
HSD17B10 Q99714 1/20 0.53
HPGD P15428 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
MAPT P10636 2/20 0.50
PKM P14618 1/20 0.50
RAB9A P51151 1/20 0.50
MAOB P27338 5/20 0.48
PYCR1 P32322 1/20 0.48
HSD17B1 P14061 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MAOA P21397 1/20 0.47
GAA P10253 1/20 0.47
EPHX2 P34913 2/20 0.46
NR1H4 Q96RI1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20314640 0.93 KMT2A (0.61) KMT2ALMNAHSD17B10HPGDL3MBTL1
Sulfuric Acid SCHEMBL28405744 0.91 KMT2A (0.59) KMT2ALMNAHSD17B10HPGDL3MBTL1
SCHEMBL28277570 0.89 KMT2A (0.57) KMT2ALMNAHSD17B10HPGDL3MBTL1
Acetophenone SCHEMBL27579748 0.84 LMNA (0.64) KMT2ALMNAHSD17B10HPGDL3MBTL1
SCHEMBL6859304 0.82 KMT2A (1.00) KMT2ALMNAHSD17B10HPGDL3MBTL1
SCHEMBL9818052 0.82 KMT2A (0.73) KMT2ALMNAHSD17B10HPGDL3MBTL1
SCHEMBL77965 0.81 KMT2A (0.64) KMT2ALMNAHSD17B10HPGDL3MBTL1
SCHEMBL50646 0.81 MAPT (0.68) KMT2ALMNAHPGDL3MBTL1MAPT
SCHEMBL7692352 0.80 KMT2A (0.70) KMT2ALMNAHSD17B10HPGDL3MBTL1
SCHEMBL334751 0.80 KMT2A (0.70) KMT2ALMNAHSD17B10HPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109678788-A A kind of 1,2- diaryl indoles, derivative and its synthetic method 湘潭大学 2019-04-26 CN claimed
US-5041567-A Human and veterianary medicine; veneral diseases respiratory diseases, bovine mastitis BEECHAM GROUP PLC (GB) 1991-08-20 US claimed
EP-4735045-A2 OXAZAPHOSPHORINE ANTIBODY DRUG CONJUGATES AND METHODS OF USE La Life Products, LLC (US) 2026-05-06 EP disclosed
EP-4709725-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Progentos Therapeutics, Inc. (US) 2026-03-18 EP disclosed
EP-4673126-A1 COMPOSITIONS AND METHODS OF USE THEREOF Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) 2026-01-07 EP disclosed
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2025-11-13 US disclosed
CN-120485985-B Method for preparing filling fiber by regenerating polyester waste silk 江苏海科纤维有限公司 2025-10-14 CN disclosed
CN-120485985-A Method for preparing filling fiber by regenerating polyester waste silk 江苏海科纤维有限公司 2025-08-15 CN disclosed
CN-120289840-A Display screen protection film and preparation method thereof 深圳尚豪实业有限公司 2025-07-11 CN disclosed
EP-4532484-A1 ROCK INHIBITORS AND USES THEREOF DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2025-04-09 EP disclosed
US-20250009900-A1 OXAZAPHOSPHORINE ANTIBODY DRUG CONJUGATES AND METHODS OF USE LA LIFE PRODUCTS, LLC (US) 2025-01-09 US disclosed
CN-1003712-B Process for preparing 6- (1-acyl-1-hydroxymethyl or acetoxymethyl) penicillanic acid derivatives 美国辉瑞有限公司 1989-03-29 CN disclosed
US-4812470-A Antibacterial monic acid derivatives BEECHAM GROUP P.L.C. (GB) 1989-03-14 US disclosed
US-4762921-A 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives PFIZER INC. (US) 1988-08-09 US disclosed
US-4731364-A Dihydrobenzo(B)thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1988-03-15 US disclosed
US-4675186-A 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives PFIZER INC. (US) 1987-06-23 US disclosed
EP-0212428-A1 Dihydrobenzo/b /thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1987-03-04 EP disclosed
EP-0201221-A1 6-(1-acyl-1-hydroxy methyl) penicillanic acid derivatives PFIZER INC. (US) 1986-11-12 EP disclosed
CN-86102736-A The preparation method and the application thereof of 6-(1-acyl group-1-methylol) penicillanic acid derivative 1986-10-15 CN disclosed
EP-0087953-A2 Antibacterial 1-normon-2-yl-heterocyclic compounds BEECHAM GROUP PLC (GB) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF ROCK1, ROCK2, RHOA KMT2A 3598/4885LMNA 2579/4885HSD17B10 1378/4885
US-20250009900-A1 OXAZAPHOSPHORINE ANTIBODY DRUG CONJUGATES AND METHODS OF USE ENTPD1, ENTPD2, ENTPD3 KMT2A 1022/4885LMNA 4445/4885HSD17B10 3500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.