Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286725 | 1.00 | SIGMAR1 (0.50) | SIGMAR1ACHEHTR1AGBA1TMEM97 | |
| SCHEMBL2885978 | 0.81 | SIGMAR1 (0.54) | SIGMAR1ACHEHTR1AGBA1 | |
| SCHEMBL9595473 | 0.76 | SIGMAR1 (0.50) | SIGMAR1ACHEHTR1AGBA1 | |
| SCHEMBL20588229 | 0.74 | ACHE (0.56) | SIGMAR1ACHEGBA1MAPT | |
| SCHEMBL6853255 | 0.74 | ACHE (0.56) | SIGMAR1ACHEGBA1MAPT | |
| SCHEMBL12204969 | 0.73 | ACHE (0.55) | SIGMAR1ACHE | |
| SCHEMBL13995018 | 0.71 | ACHE (0.53) | SIGMAR1ACHEGBA1MAPT | |
| SCHEMBL8301747 | 0.71 | HTR1A (0.51) | SIGMAR1ACHEHTR1AGBA1 | |
| SCHEMBL14417820 | 0.71 | ACHE (0.53) | SIGMAR1ACHEGBA1MAPT | |
| SCHEMBL3176956 | 0.71 | HTR1A (0.51) | SIGMAR1ACHEHTR1AGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114925-B1 | AZETIDINE ANALOGUES OF NUCLEOSIDASE AND PHOSPHORYLASE INHIBITORS | IND RES LTD (NZ) | 2012-04-11 | — | — | EP | disclosed |