Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.57 |
| ▸ | WNT3A | P56704 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001632 | 0.85 | MKNK1 (0.54) | MKNK1MKNK2WNT3AHTTLMNA | |
| SCHEMBL3933089 | 0.85 | ALDH1A1 (0.60) | KDM4ENPC1ALDH1A1MAPK1MKNK1 | |
| SCHEMBL12646562 | 0.85 | HDAC1 (0.60) | KDM4ENPC1ALDH1A1MAPK1MKNK1 | |
| SCHEMBL28303354 | 0.83 | MKNK1 (0.62) | ALDH1A1MKNK1MKNK2WNT3AHTT | |
| SCHEMBL29466814 | 0.82 | NAPRT (0.62) | KDM4ENPC1ALDH1A1MAPK1CYP19A1 | |
| SCHEMBL178130 | 0.82 | NAPRT (0.62) | KDM4ENPC1ALDH1A1MAPK1CYP19A1 | |
| SCHEMBL1428025 | 0.82 | LMNA (0.62) | KDM4ENPC1ALDH1A1HTTLMNA | |
| SCHEMBL3932055 | 0.82 | ALDH1A1 (0.60) | KDM4ENPC1ALDH1A1MAPK1MKNK1 | |
| SCHEMBL3941801 | 0.81 | ALDH1A1 (0.58) | KDM4ENPC1ALDH1A1MAPK1LMNA | |
| Ammonia Solution, Strong SCHEMBL27841922 | 0.81 | NAPRT (0.61) | KDM4ENPC1ALDH1A1MAPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7883713-B2 | Suspension, ointment, solution, spray, lotion, gel, cream, powder, powder spray, paste, emulsion, foam or stick; for treatment of herpes infections in humans | AICURIS GMBH & CO. KG (DE) | 2011-02-08 | — | — | US | disclosed |
| US-7883713-B2 | Suspension, ointment, solution, spray, lotion, gel, cream, powder, powder spray, paste, emulsion, foam or stick; for treatment of herpes infections in humans | AICURIS GMBH & CO. KG (DE) | 2011-02-08 | — | — | US | disclosed |
| EP-1629842-B1 | Topical application of thiazolyl amides | AICURIS GMBH & CO KG (DE) | 2010-04-14 | — | — | EP | disclosed |