Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444019 | 0.77 | — | — | |
| SCHEMBL1153007 | 0.66 | MAP3K14 (0.35) | MAP3K14ALDH1A1POLB | |
| SCHEMBL12703009 | 0.66 | ALDH1A1 (0.32) | MAP3K14ALDH1A1POLB | |
| SCHEMBL1153528 | 0.61 | GSK3B (0.37) | MAP3K14ALDH1A1POLB | |
| SCHEMBL12658141 | 0.58 | CSNK2A2 (0.38) | MAP3K14ALDH1A1POLB | |
| SCHEMBL1153876 | 0.57 | PDE7A (0.41) | MAP3K14ALDH1A1 | |
| SCHEMBL31414474 | 0.55 | CA12 (0.57) | ALDH1A1 | |
| SCHEMBL14613145 | 0.55 | ERN1 (0.56) | MAP3K14ALDH1A1 | |
| SCHEMBL13342911 | 0.55 | LMNA (0.55) | ALDH1A1POLB | |
| SCHEMBL11425977 | 0.55 | MAP3K14 (0.46) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | MAP3K14 920/4885ALDH1A1 2306/4885POLB 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.